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Updated: Jun 5, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
2-Methyl-5-(4-tol-yl)-7-(trifluoro-meth-yl)pyrazolo[1,5-a]pyrimidine
Clarissa P Frizzo1, Patrick T Campos, Mara R B Marzari
1Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97105-900, Santa Maria, RS, Brazil.
Abstract:
In the title compound, C(15)H(12)F(3)N(3), the pyrazolo[1,5-a]pyrimidine system ring is essentially planar with a maximum deviation from the mean plane of 0.014 (1) Å. The 4-tolyl group makes a dihedral angle of 14.1 (1)° with the pyrazolo[1,5-a]pyrimidine ring system. The crystal packing is stabilized mainly by van der Waals forces.
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