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Related Concept Videos

Proton (¹H) NMR: Chemical Shift01:07

Proton (¹H) NMR: Chemical Shift

Organic molecules primarily contain carbon and hydrogen atoms. While all the hydrogen isotopes are NMR-active, protium or hydrogen-1 is the most abundant. It has a significant energy separation between its nuclear spin states due to its large gyromagnetic ratio. As per Boltzmann's distribution, an increase in the energy separation implies a greater excess population of nuclei available for excitation, resulting in a strong NMR absorption signal.
Absorption signals of all the protium nuclei in a...
Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.
IUPAC Nomenclature of Aldehydes01:16

IUPAC Nomenclature of Aldehydes

Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...
2° Amines to N-Nitrosamines: Reaction with NaNO201:20

2° Amines to N-Nitrosamines: Reaction with NaNO2

Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.
Electron Paramagnetic Resonance (EPR) Spectroscopy: Organic Radicals01:17

Electron Paramagnetic Resonance (EPR) Spectroscopy: Organic Radicals

Ideally, an unpaired electron shows a single peak in the EPR spectrum due to the transition between the two spin energy states. However, coupling interactions can occur between the spins of the unpaired electron and any neighboring spin-active nuclei. This hyperfine coupling results in hyperfine splitting, where the EPR signal is split into multiplets. The signals split into 2nI + 1 peaks, where n is the number of equivalent nuclei and I is the nuclear spin. These splitting patterns provide...
Conjugate Addition of Enolates: Michael Addition01:08

Conjugate Addition of Enolates: Michael Addition

The attack of a nucleophile at the β carbon of an α,β-unsaturated carbonyl compound is called conjugate addition. Conjugate addition reactions of active methylene compounds, such as β-diketones, β-keto esters, β-keto nitriles, and α-nitro ketones, are called Michael addition reactions.

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Related Experiment Video

Updated: Jun 5, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
06:46

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

(E)-Methyl 2-[(4-nitro-phen-yl)-hydrazono]-propanoate.

Hai-Yang Yu1, Xin Fang, Ming-Lei Cao

  • 1Department of Chemistry, University of Fuzhou, Fuzhou 350002, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
PubMed
Summary
This summary is machine-generated.

This study details a novel chemical compound, a condensation product of 4-nitro-phenyl-hydrazine and methyl pyruvate. Its structure features a planar conjugated system stabilized by hydrogen bonding and π-π interactions.

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Preparation of N-(2-alkoxyvinyl)sulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Last Updated: Jun 5, 2026

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A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

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Area of Science:

  • Organic Chemistry
  • Crystallography

Background:

  • 4-nitro-phenyl-hydrazine and methyl pyruvate are common organic precursors.
  • Condensation reactions are fundamental in synthesizing complex organic molecules.

Purpose of the Study:

  • To synthesize and characterize a novel organic compound.
  • To investigate the structural and electronic properties of the synthesized molecule.

Main Methods:

  • Chemical synthesis via condensation reaction.
  • Single-crystal X-ray diffraction for structural analysis.
  • Computational methods to analyze the electronic structure.

Main Results:

  • The title compound, C(10)H(11)N(3)O(4), was successfully synthesized.
  • The molecule exhibits an approximate planar conformation with a conjugated π system.
  • Crystal packing analysis revealed N-H⋯O hydrogen bonds and π-π interactions between aromatic rings (centroid-centroid distance: 3.617 Å).

Conclusions:

  • The synthesized compound possesses a unique planar conjugated structure.
  • Intermolecular interactions play a significant role in the crystal packing and stability.
  • The study provides insights into the structure-property relationships of nitro-phenyl-hydrazine derivatives.