Related Experiment Video
Updated: Jun 5, 2026
14:18
A Strategy for Sensitive, Large Scale Quantitative Metabolomics
Published on: May 27, 2014
2-Methyl-2-(4-nitro-phenyl-sulfanyl)-propanoic acid.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study investigates a novel compound, C(10)H(11)NO(4)S, exploring its potential biological activity. Molecular analysis reveals specific hydrogen bonding patterns that influence its crystal structure and interactions.
Area of Science:
- Crystallography
- Chemical analysis
- Biological activity
Background:
- The compound C(10)H(11)NO(4)S is of interest due to its potential biological activity.
- Understanding the molecular structure and intermolecular interactions is crucial for predicting and optimizing biological function.
Purpose of the Study:
- To characterize the crystal structure of C(10)H(11)NO(4)S.
- To investigate the intermolecular interactions, specifically hydrogen bonding, within the crystal lattice.
- To provide a foundation for further studies on the biological activity of this compound.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of intermolecular interactions, including hydrogen bonds (O-H⋯O) and weak C-H⋯O interactions, was performed.
Main Results:
- The title compound, C(10)H(11)NO(4)S, forms centrosymmetric dimers through intermolecular O-H⋯O hydrogen bonds.
- These dimers are further organized into chains via weaker C-H⋯O interactions.
- The detailed crystal structure provides insights into the compound's solid-state organization.
Conclusions:
- The elucidated crystal structure and intermolecular interactions of C(10)H(11)NO(4)S are key to understanding its physical properties.
- This structural information serves as a basis for exploring its potential biological activities.
- Further research can build upon these findings to develop applications based on this compound.
Related Concept Videos
01:16IUPAC Nomenclature of Aldehydes
Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...
01:16Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides
Naming Acid Halides
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
03:02Organic Compounds
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
01:11Nomenclature of Carboxylic Acid Derivatives: Amides and Nitriles
Naming Amides
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
01:07Proton (¹H) NMR: Chemical Shift
Organic molecules primarily contain carbon and hydrogen atoms. While all the hydrogen isotopes are NMR-active, protium or hydrogen-1 is the most abundant. It has a significant energy separation between its nuclear spin states due to its large gyromagnetic ratio. As per Boltzmann's distribution, an increase in the energy separation implies a greater excess population of nuclei available for excitation, resulting in a strong NMR absorption signal.
Absorption signals of all the protium nuclei in a...
Absorption signals of all the protium nuclei in a...
01:202° Amines to N-Nitrosamines: Reaction with NaNO2
Secondary amines react with nitrous acid to form N-nitrosamines, as depicted in Figure 1. Nitrous acid, a weak and unstable acid, is formed in situ from an aqueous solution of sodium nitrite and strong acids, such as hydrochloric acid or sulfuric acid, in cold conditions. In the presence of an acid, the nitrous acid gets protonated. The subsequent loss of water results in the formation of the electrophile known as nitrosonium ion.