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Updated: Jun 5, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
2,6-Dimethyl-4-m-tolyl-cyclo-hex-3-enecarboxylic acid
Abstract:
The title compound, C(16)H(20)O(2), was synthesized to study the hydrogen-bonding inter-action of the two enanti-omers in the solid state. The racemate is made up of carboxylic acid RS dimers. Inter-molecular O-H⋯O hydrogen bonds produce centrosymmetric R(2) (2)(8) rings which dimerize the two chiral enanti-omers through their carboxyl groups. The chirality of this compound is generated by the presence of the double bond in the cyclo-hexene ring and a chiral axis due to the meta-methyl substituent on the aromatic ring.
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