N-(4-Chloro-2-nitro-phen-yl)methane-sulfonamide.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study details a new chemical compound, C(7)H(7)ClN(2)O(4)S, a potential precursor for biologically active substituted quinolines. Its crystal structure reveals specific bonding and packing arrangements important for chemical synthesis.
Area of Science:
- Organic Chemistry
- Crystallography
- Medicinal Chemistry
Background:
- Substituted quinolines are important in medicinal chemistry.
- N-phenyl-methane sulfonamides serve as valuable chemical precursors.
- Understanding precursor structures aids in designing new biologically active compounds.
Purpose of the Study:
- To characterize the chemical structure of a novel compound, C(7)H(7)ClN(2)O(4)S.
- To investigate its potential as a precursor for substituted quinolines.
- To analyze its structural features, including hydrogen bonding and crystal packing.
Main Methods:
- Chemical synthesis of the title compound.
- X-ray crystallography for structural determination.
- Analysis of intra-molecular and inter-molecular interactions.
Main Results:
- The compound C(7)H(7)ClN(2)O(4)S was synthesized and structurally characterized.
- An intra-molecular N-H⋯O hydrogen bond forms a six-membered ring.
- Inter-molecular C-H⋯O contacts contribute to crystal stabilization.
Conclusions:
- The characterized compound is a promising precursor for biologically active substituted quinolines.
- The detailed structural information provides insights for synthetic modifications.
- The findings contribute to the field of organic synthesis and drug discovery.
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