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Updated: Jun 5, 2026
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Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
(E)-1-Ferrocenyl-3-(4-methoxy-phen-yl)-prop-2-en-1-one
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study details a novel iron compound with bridged cyclopentadienyl and benzene rings. The molecule forms a unique three-dimensional framework through various intermolecular interactions, including hydrogen bonds and pi-interactions.
Area of Science:
- Organometallic Chemistry
- Crystallography
- Supramolecular Chemistry
Background:
- Ferrocene derivatives are crucial in catalysis and materials science.
- Understanding intermolecular forces is key to designing novel crystal structures.
- Conjugated systems in organometallic compounds influence electronic properties.
Purpose of the Study:
- To synthesize and characterize a novel ferrocene derivative with a conjugated substituent.
- To investigate the crystal structure and intermolecular interactions of the title compound.
- To explore the self-assembly behavior driven by hydrogen bonding and pi-interactions.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
- Spectroscopic methods were used for compound characterization (details not provided in abstract).
- Analysis of intermolecular interactions, including hydrogen bonds and C-H···π interactions.
Main Results:
- The title compound, [Fe(C(5)H(5))(C(15)H(13)O(2))], features eclipsed and nearly parallel cyclopentadienyl rings within the ferrocene core.
- An intramolecular C-H⋯O hydrogen bond forms an S(5) motif.
- A three-dimensional framework is established through five intermolecular C-H⋯O hydrogen bonds and one C-H⋯π(Cps) interaction.
Conclusions:
- The study successfully synthesized and characterized a novel ferrocene derivative.
- The crystal packing is significantly influenced by a combination of intra- and intermolecular hydrogen bonds and C-H⋯π interactions.
- The findings contribute to the understanding of supramolecular assembly in organometallic compounds.
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