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06:46
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
(E,E)-2,2'-[1,1'-(Cyclohexane-1,2-diyl-dinitrilo)diethylidyne]diphenol
1Ordered Matter Science Research Center, College of Chemistry and Chemical Engineering, Southeast University, Nanjing 210096, People's Republic of China.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study details the crystal structure of a chiral compound, C(22)H(26)N(2)O(2). The analysis reveals two independent molecules within the asymmetric unit, exhibiting specific symmetry relationships and intermolecular interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure Analysis
Background:
- Chiral compounds are crucial in various scientific fields.
- Understanding molecular arrangements provides insights into chemical properties.
- Input reagents' known chirality dictates the absolute configuration of the title compound.
Purpose of the Study:
- To elucidate the crystal structure of the chiral compound C(22)H(26)N(2)O(2).
- To determine the absolute configuration based on precursor molecules.
- To investigate intermolecular and intramolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction analysis.
- Determination of the asymmetric unit content.
- Analysis of molecular symmetry and bonding parameters.
Main Results:
- The asymmetric unit contains two crystallographically independent molecules in distinct orientations.
- A non-crystallographic twofold rotation axis relates the two molecules, with each exhibiting a pseudo-twofold axis.
- Observed intermolecular C-H⋯π(ring) interactions and intramolecular O-H⋯N hydrogen bonds.
Conclusions:
- The crystal structure of C(22)H(26)N(2)O(2) has been successfully determined.
- The compound's chirality and absolute configuration are confirmed.
- Specific intermolecular and intramolecular interactions influence the crystal packing.
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01:16[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction
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In cyclohexane, the substituents can occupy different positions generating distinct isomers.
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