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N-(3,4-Difluoro-phen-yl)-2-(3,4-dimethoxy-phen-yl)acetamide
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
The crystal structure of a novel amide, C(16)H(15)F(2)NO(3), reveals a dihedral angle of 53.7° between its benzene rings. Molecules form a 1D network via intermolecular N-H⋯O hydrogen bonds.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding the solid-state structure of organic molecules is crucial for predicting their physical and chemical properties.
- Amide functionalities are known to participate in various intermolecular interactions, influencing crystal packing.
Purpose of the Study:
- To elucidate the crystal structure of the title amide, C(16)H(15)F(2)NO(3).
- To investigate the intermolecular interactions governing the crystal packing and network formation.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding and other non-covalent interactions was performed.
Main Results:
- The crystal structure of C(16)H(15)F(2)NO(3) was determined, showing a dihedral angle of 53.7(1)° between the two benzene rings.
- Molecules are linked by intermolecular N-H⋯O hydrogen bonds, forming a one-dimensional (1D) network along the [001] direction.
- No significant inter-chain contacts were observed, indicating the isolated nature of the 1D chains.
Conclusions:
- The crystal packing of the title amide is dominated by intermolecular N-H⋯O hydrogen bonds.
- The formation of a 1D network structure is a key feature of this amide's solid state.
- The observed structure provides insights into the supramolecular assembly of fluorinated amides.
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