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Updated: Jun 5, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
2,5,7-Trimethyl-3-phenyl-sulfonyl-1-benzofuran
Abstract:
The title compound, C(17)H(16)O(3)S, was prepared by the oxidation of 2,5,7-trimethyl-3-phenyl-sulfanyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring exhibits a dihedral angle of 81.16 (4)° with the plane of the benzofuran fragment. The crystal structure is stabilized by π-π inter-actions between the furan and benzene rings of neighbouring mol-ecules [centroid-centroid distance = 3.874 (2) Å] and by C-H⋯π inter-actions between a phenyl H atom of the phenyl-sulfonyl substituent and the furan ring of adjacent mol-ecules. In addition, the crystal structure exhibits intra- and inter-molecular C-H⋯O inter-actions.
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