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l-Alanine hydrochloride monohydrate.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
Researchers crystallized l-alanine hydrochloride monohydrate from a powder sample. The crystal structure reveals extensive intermolecular hydrogen bonding involving hydroxyl, ammonium, chloride, and water groups.
Area of Science:
- Crystallography
- Chemical Physics
- Materials Science
Background:
- Amino acids and their derivatives are fundamental building blocks in biochemistry.
- Understanding the solid-state structure of amino acid salts is crucial for pharmaceutical and materials applications.
- l-Alanine hydrochloride monohydrate is a derivative with potential applications in various chemical processes.
Purpose of the Study:
- To characterize the crystal structure of l-alanine hydrochloride monohydrate.
- To investigate the intermolecular interactions, particularly hydrogen bonding, within the crystal lattice.
- To provide insights into the solid-state behavior of amino acid salts.
Main Methods:
- Single crystal X-ray diffraction was employed to determine the atomic arrangement.
- The crystal sample was obtained by allowing a powder sample to stand in a refrigerator.
- Analysis of the diffraction data yielded the precise molecular and crystal structure.
Main Results:
- Colorless crystals of l-alanine hydrochloride monohydrate (C(3)H(8)NO(2) (+)·Cl(-)·H(2)O) were successfully obtained and analyzed.
- The crystal structure is characterized by extensive intermolecular hydrogen bonding networks.
- Specific hydrogen bonds were identified between the hydroxyl group and chloride, the ammonium group and chloride, and the ammonium group and water molecules.
Conclusions:
- The detailed crystal structure of l-alanine hydrochloride monohydrate has been elucidated.
- The study highlights the significant role of hydrogen bonding in stabilizing the crystal structure.
- These findings contribute to the understanding of molecular interactions in crystalline amino acid derivatives.
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