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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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4-Hydr-oxy-3-nitro-benzaldehyde.
Mohd Razali Rizal1, Isha Azizul, Seik Weng Ng
1Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study reveals how hydroxyl groups in C(7)H(5)NO(4) molecules form hydrogen bonds, creating linear chains. These molecular interactions influence the compound's crystal structure and chemical properties.
Area of Science:
- Crystallography
- Molecular Chemistry
Background:
- Understanding intermolecular forces is crucial for predicting material properties.
- The title compound, C(7)H(5)NO(4), presents an interesting case for studying hydrogen bonding interactions.
Purpose of the Study:
- To elucidate the hydrogen bonding network in the title compound, C(7)H(5)NO(4).
- To characterize the resulting supramolecular structure and analyze molecular conformations.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bond distances and angles provided insights into the bonding interactions.
Main Results:
- Two independent molecules of C(7)H(5)NO(4) were identified in the crystal lattice.
- Each molecule exhibits intra-molecular and inter-molecular O-H⋯O hydrogen bonds involving hydroxyl, nitro, and aldehyde groups.
- These interactions lead to the formation of a linear chain supramolecular structure.
- The dihedral angles between the aromatic ring and the nitro group were found to be 10.9(3)° and 9.9(2)° for the two molecules.
Conclusions:
- The hydrogen bonding pattern in C(7)H(5)NO(4) dictates a linear chain assembly.
- The observed conformations and bonding provide a foundation for understanding the compound's physical and chemical behavior.
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