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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
4'-Fluoro-2'-hydroxy-acetophenone.
Mohd Razali Rizal1, Seik Weng Ng
1Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study investigates the molecular structure of C(8)H(7)FO(2). Findings suggest an intramolecular hydrogen bond influences the compound's conformation.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure
Background:
- Understanding molecular conformation is crucial in organic chemistry.
- Hydrogen bonding plays a significant role in dictating molecular geometry.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(8)H(7)FO(2).
- To investigate the potential influence of intramolecular hydrogen bonding on molecular conformation.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed.
- The crystallographic data were analyzed to determine molecular geometry.
Main Results:
- The title compound, C(8)H(7)FO(2), crystallizes as discrete molecules.
- An intramolecular hydroxy-carbonyl O-H⋯O hydrogen bond was identified.
- This hydrogen bond may influence the observed molecular conformation.
Conclusions:
- The crystal structure of C(8)H(7)FO(2) reveals discrete molecular units.
- Intramolecular hydrogen bonding is a key feature affecting the molecule's conformation.
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