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Updated: Jun 5, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(S)-N-(1-Hydroxy-methyl-2-methyl-prop-yl)-2-methoxy-benzamide
Jihong Li1, Wenhai Wang, Jingbo Lan
1Key Laboratory of Green Chemistry and Technology of the Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, People's Republic of China.
This study details a chemical compound, C(13)H(19)NO(3), identified as a crucial intermediate in synthetic processes. Its crystal structure is notably stabilized by specific hydrogen bonding interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- The title compound, C(13)H(19)NO(3), is recognized for its utility as a synthetic intermediate.
- Understanding the factors influencing crystal structure stability is vital in chemical synthesis and materials development.
Purpose of the Study:
- To characterize the crystal structure of the compound C(13)H(19)NO(3).
- To investigate the role of intermolecular forces, specifically hydrogen bonding, in stabilizing the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of the crystal structure involved identifying and quantifying hydrogen bonding interactions.
Main Results:
- The crystal structure of C(13)H(19)NO(3) was successfully elucidated.
- Weak O-H⋯O and N-H⋯O hydrogen bonds were identified as key stabilizing forces within the crystal lattice.
Conclusions:
- The compound C(13)H(19)NO(3) possesses a stable crystal structure.
- Hydrogen bonding plays a significant role in the structural integrity of this important synthetic intermediate.
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