Related Experiment Video
Updated: Jun 5, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Benzoyl-methyl pyridine-4-carboxyl-ate
The crystal structure of a novel organic compound, C(14)H(11)NO(3), was determined. Molecular packing is stabilized by C-H⋯π interactions between phenyl and pyridine rings.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding molecular interactions is key in crystal engineering.
- Organic synthesis provides novel compounds for structural analysis.
Purpose of the Study:
- To determine the crystal structure of the title compound, C(14)H(11)NO(3).
- To investigate the intermolecular interactions stabilizing the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to elucidate the crystal structure.
- The compound was synthesized via reaction of 2-bromo-1-phenyl-ethanone and pyridine-4-carboxylic acid.
Main Results:
- The molecular structure revealed a C(14)H(11)NO(3) formula.
- Crystal packing is significantly influenced by C-H⋯π interactions between phenyl and pyridine rings.
- Key torsion angles (C-C-O-C: -80.8(2)°) and dihedral angles (phenyl-pyridyl: 65.8(1)°) were quantified.
Conclusions:
- The study successfully characterized the crystal structure of C(14)H(11)NO(3).
- C-H⋯π interactions play a crucial role in the observed molecular packing and crystal stability.
Related Concept Videos
Carboxylic Acids to Methylesters: Alkylation using Diazomethane
Electrophilic Aromatic Substitution: Sulfonation of Benzene
Reactions at the Benzylic Position: Oxidation and Reduction
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism
Electrophilic Aromatic Substitution: Nitration of Benzene
Electrophilic Aromatic Substitution: Friedel–Crafts Acylation of Benzene

