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Updated: Jun 5, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
3-[4-(Dimethyl-amino)phen-yl]-1-(2-pyrrol-yl)prop-2-en-1-one
Si-Ping Tang1, Dai-Zhi Kuang, Yong-Lan Feng
1Department of Chemistry and Materials Science, Hengyang Normal University, Hengyang, Hunan 421008, People's Republic of China.
Abstract:
The molecule of the title compound, C(15)H(16)N(2)O, is non-planar with a dihedral angle of 16.0 (1)° between the pyrrole and benzene rings. The ketone double-bond displays an s-cis conformation with an O=C-C=C torsion angle of 7.9 (3) and an intramolecular C-H⋯O hydrogen bond. In the crystal structure, adjacent mol-ecules are paired through N-H⋯O hydrogen bonds into centrosymmetric dimers.
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