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(2,4-Dimethoxy-benzyl-idene)-2-hydroxy-benzohydrazide ethanol solvate
Wagee A Yehye1, Azhar Ariffin, Seik Weng Ng
1Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
This study reveals a planar Schiff base molecule forming a hydrogen-bonded dimer with an ethanol solvent molecule via a hydroxy-amide interaction. This interaction involves the ethanol
Area of Science:
- Crystal Engineering
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Schiff base molecules are versatile organic compounds with diverse applications.
- Hydrogen bonding plays a crucial role in the self-assembly and structural organization of molecules.
- Understanding solvent-solute interactions is key to controlling crystal structures.
Purpose of the Study:
- To investigate the crystal structure of a specific Schiff base molecule.
- To elucidate the role of ethanol as a solvent in the formation of hydrogen-bonded networks.
- To characterize the nature of intermolecular interactions in the solid state.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding and intermolecular contacts was performed.
- The molecular formula C(16)H(16)N(2)O(4)·C(2)H(6)O was confirmed.
Main Results:
- The title molecule crystallizes as a planar Schiff base linked to an ethanol solvent molecule.
- A significant hydroxy-amide hydrogen bond was observed between the Schiff base and ethanol.
- A hydrogen-bonded dimer was formed across a center of symmetry, involving ethanol's hydroxyl group and the Schiff base's imine nitrogen.
Conclusions:
- The study successfully characterized the crystal structure and supramolecular assembly of the Schiff base-ethanol adduct.
- The findings highlight the importance of specific hydrogen bonding in directing crystal packing and dimer formation.
- This work contributes to the understanding of Schiff base crystal engineering and solvent-mediated self-assembly.
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