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Updated: Jun 5, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
t-3-Benzyl-r-2,c-6-bis-(4-methoxy-phen-yl)-piperidin-4-one
Abstract:
In the title compound, C(26)H(27)NO(3), the piperidine ring adopts a chair conformation. The two methoxy-phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations and make a dihedral angle of 87.33 (8)°. The benzyl group at position 3 has an equatorial orientation. The phenyl ring of the benzyl group makes dihedral angles of 75.60 (9) and 73.69 (9)° with the two benzene rings. Mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds and by C-H⋯π inter-actions.
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