Related Experiment Video

Updated: Jun 5, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
11:04

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

Published on: June 13, 2022

2-(Tricyclo[3.3.1.1]dec-2-ylamino)ethanol hemihydrate

Grant A Boyle, Thavendran Govender, Hendrik G Kruger

    Acta Crystallographica. Section E, Structure Reports Online
    |January 5, 2011
    PubMed

    More Related Videos

    Modification and Functionalization of the Guanidine Group by Tailor-made Precursors09:45

    Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

    Published on: April 27, 2017

    Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles11:45

    Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

    Published on: August 22, 2018

    Related Concept Videos

    Aldehydes and Ketones with Alcohols: Hemiacetal Formation01:19

    Aldehydes and Ketones with Alcohols: Hemiacetal Formation

    Similar to water, alcohols can add to the carbonyl carbon of the aldehydes and ketones. The addition of one molecule of alcohol to the carbonyl compound forms the hemiacetal or half acetal. As depicted below, in a hemiacetal, the carbon is directly linked to an OH and OR group.
    Aldehydes and Ketones with Water: Hydrate Formation01:20

    Aldehydes and Ketones with Water: Hydrate Formation

    An oxygen-based nucleophile, like water, can undergo addition reactions with aldehydes and ketones. The reaction leads to the formation of hydrates, also referred to as 1,1-diols or geminal diols.
    The formation of hydrates is a reversible reaction. Hydrate formation is influenced by steric and electronic factors accompanying the alkyl substituents on the carbonyl group: The rate of hydrate formation increases with a decrease in the number of alkyl groups attached to the carbonyl carbon. Hence,...
    Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis02:29

    Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis

    Overview
    Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
    Preparation of Ethers by Alcohol Dehydration
    In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
    Structure and Nomenclature of Ethers02:28

    Structure and Nomenclature of Ethers

    Structure and Bonding
    Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
    Classification of Ethers
    Based on their attached substituent groups, ethers can be classified into two...
    Acidity and Basicity of Alcohols and Phenols02:36

    Acidity and Basicity of Alcohols and Phenols

    Like water, alcohols are weak acids and bases. This is attributed to the polarization of the O–H bond making the hydrogen partially positive. Moreover, the electron pairs on the oxygen atom of alcohol make it both basic and nucleophilic. Protonation of an alcohol converts hydroxide, a poor leaving group, into water—a good one. The two acid–base equilibria corresponding to ethanol are depicted below.
    Alkylation of β-Diester Enolates: Malonic Ester Synthesis01:14

    Alkylation of β-Diester Enolates: Malonic Ester Synthesis

    Malonic ester synthesis is a method to obtain α substituted carboxylic acids from ꞵ-diesters such as diethyl malonate and alkyl halides.