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Updated: Jun 5, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
2-[4-Benzyl-5-(2-fur-yl)-4H-1,2,4-triazol-3-ylsulfan-yl]acetamide
Abstract:
In the title compound, C(15)H(14)N(4)O(2)S, the phenyl ring is inclined at 70.25 (6)° with respect to the approximately planar fur-yl-triazolsulfan-yl-acetamide unit. In the crystal structure, mol-ecules related by inversion centers form dimers via inter-molecular N-H⋯O hydrogen bonds between acetamide groups, resulting in eight-membered rings with an R(2) (2)(8) motif. In addition, the other H atom of the acetamide group is involved in an inter-molecular hydrogen bond with an N atom of the triazole ring, resulting in chains extended along the c axis. The overall effect is the formation of a hydrogen-bonded two-dimensional framework perpendicular to the a axis.
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