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Updated: Jun 5, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2-[(E)-(5-Amino-2,3-diphenyl-quinoxalin-6-yl)imino-meth-yl]-4-chloro-phenol
Abstract:
The title Schiff base compound, C(27)H(19)ClN(4)O, features two intra-molecular O-H⋯N and N-H⋯N hydrogen bonds involving the hydr-oxy and amino groups to generate S(6) and S(5) ring motifs, respectively. In the crystal structure, weak inter-molecular N-H⋯O and C-H⋯N inter-actions, together with π-π contacts [centroid-centroid distances = 3.6294 (11)-3.6881 (11) Å], link neighboring mol-ecules.
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