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Updated: Jun 5, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
N'-(3,5-Di-tert-butyl-4-hydroxy-benzyl-idene)-2-hydroxy-benzohydrazide methanol solvate
Wagee A Yehye1, Azhar Ariffin, Seik Weng Ng
1Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Abstract:
The asymmetric unit of the title compound, C(22)H(28)N(2)O(3)·CH(4)O, consists of two independent Schiff base mol-ecules and two independent methanol solvent mol-ecules. In one Schiff base mol-ecule, the 2-hydr-oxy group forms an intra-molecular hydrogen bond with the amide O atom, whereas in the other Schiff base mol-ecule, the 2-hydr-oxy-substituted benzene ring is oriented so that the 2-hydr-oxy group serves as hydrogen-bond acceptor for the amide NH group. In the crystal structure, Schiff base mol-ecules inter-act with methanol solvent to furnish a hydrogen-bonded chain.
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