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Updated: Jun 5, 2026

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Dynamic cylindrical assembly of triblock copolymers by a hierarchical process of covalent and supramolecular
1Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States.
Abstract:
We have developed a hierarchical process that combines linear triblock copolymers into concentric globular subunits through strong chemical bonds and is followed by their supramolecular assembly via weak noncovalent interactions to afford one-dimensionally assembled, dynamic cylindrical nanostructures. The molecular brush architecture forces triblock copolymers to adopt intramolecular interactions within confined frameworks and then drives their intermolecular interactions in the mixtures of organic solvent and water. In contrast, the triblock copolymers, when not preconnected into the molecular brush architectures, organize only into globular assemblies.
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