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Updated: Jun 5, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Early computed tomography compared with bone scintigraphy in suspected scaphoid fractures
Steven J Rhemrev1, Andele D de Zwart, Lucas M Kingma
1Department of Surgery, Medical Centre Haaglanden, The Hague, The Netherlands. s.rhemrev@mchaaglanden.nl
Early multidetector computed tomography (CT) is not superior to bone scintigraphy for diagnosing occult scaphoid fractures. Both imaging methods have limitations in detecting these subtle wrist injuries.
Area of Science:
- Orthopedic surgery
- Radiology
- Emergency medicine
Background:
- Occult scaphoid fractures are challenging to diagnose, often requiring advanced imaging.
- Early diagnosis is crucial to prevent complications like avascular necrosis.
Purpose of the Study:
- To compare the diagnostic efficacy of multidetector computed tomography (CT) versus bone scintigraphy for occult scaphoid fractures.
- To determine if CT offers superior diagnostic accuracy in the early detection of these fractures.
Main Methods:
- 100 patients with suspected scaphoid fractures underwent both CT (within 24 hours) and bone scintigraphy (3-5 days post-injury).
- A reference standard, including follow-up, was used to confirm true fractures.
- Diagnostic performance metrics (sensitivity, specificity, accuracy, PPV, NPV) were calculated for both modalities.
Main Results:
- Bone scintigraphy demonstrated higher sensitivity (93%) and negative predictive value (99%) for scaphoid fractures compared to CT (64% sensitivity, 94% NPV).
- CT showed higher specificity (99%) and positive predictive value (90%) than bone scintigraphy (91% specificity, 62% PPV).
- Overall accuracy was comparable: CT (94%) and bone scintigraphy (91%).
Conclusions:
- This study did not find multidetector computed tomography (CT) to be superior to bone scintigraphy for diagnosing suspected occult scaphoid fractures.
- Bone scintigraphy appears more sensitive in detecting these fractures, while CT offers higher specificity.
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