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Updated: Jun 5, 2026

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Early computed tomography compared with bone scintigraphy in suspected scaphoid fractures
Steven J Rhemrev1, Andele D de Zwart, Lucas M Kingma
1Department of Surgery, Medical Centre Haaglanden, The Hague, The Netherlands. s.rhemrev@mchaaglanden.nl
Purpose:
This study examined whether multidetector computed tomography (CT) is superior to bone scintigraphy for diagnosis of an occult scaphoid fracture.
Methods And Materials:
In a study period of 22 months, 100 consecutive patients with a clinically suspected scaphoid fracture and no fracture on scaphoid radiographs, were evaluated with CT within 24 hours after injury and bone scintigraphy between 3 and 5 days after injury. The reference standard for a true (radiographic occult) scaphoid fracture was either (1) diagnosis of fracture on both CT and bone scintigraphy or (2) in case of discrepancy, clinical and/or radiographic evidence of a fracture during follow-up.
Results:
CT showed 10 scaphoid and 18 other fractures. Bone scintigraphy showed 21 scaphoid and 36 other fractures. According to the reference standard, there were 14 scaphoid fractures. CT had a sensitivity of 64%, specificity of 99%, accuracy of 94%, a positive predictive value of 90%, and a negative predictive value of 94%. Bone scintigraphy had a sensitivity of 93%, specificity of 91%, accuracy of 91%, a positive predictive value of 62%, and a negative predictive value of 99%.
Conclusion:
This study could not confirm that early CT imaging is superior to bone scintigraphy for suspected scaphoid fractures.
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