Viridans streptococcal meningitis following penetrating cervical injury

Joseph B Cantey1, Pranita Tamma

  • 1Department of Pediatrics, Johns Hopkins Hospital, Baltimore, MD, USA. jbcantey@gmail.com

Pediatric Emergency Care
|January 6, 2011
PubMed

Insights

This case report details Streptococcus salivarius meningitis in a child following neck trauma. It emphasizes the risk of meningitis with cerebrospinal fluid leaks and unrecognized pneumocephalus.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

  • Viridans streptococcal meningitis is uncommon, typically linked to medical procedures or weakened immune systems.
  • Streptococcus salivarius is a rare cause of meningitis, especially in otherwise healthy individuals.

Observation:

  • A healthy child developed meningitis after neck lacerations from a fall onto a drinking glass.
  • Initial presentation was deceptive, with pneumocephalus on CT scan initially missed.
  • The patient returned within 24 hours with symptoms of meningismus (stiff neck).

Findings:

  • The case demonstrates meningitis caused by Streptococcus salivarius following penetrating neck trauma.
  • Pneumocephalus, a sign of potential cerebrospinal fluid leak, was a critical but initially unrecognized finding.
  • Cerebrospinal fluid leaks significantly increase the risk of meningitis.

Implications:

  • Highlights the importance of recognizing radiographic signs of traumatic fistulas, such as pneumocephalus.
  • Underscores the heightened risk of meningitis in patients with cerebrospinal fluid leaks.
  • This is the first reported instance of viridans streptococcal meningitis secondary to penetrating neck trauma.

Related Concept Videos

Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...