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Updated: Jun 5, 2026

Acute Myocardial Infarction in Rats

Acute Myocardial Infarction in Rats

Published on: February 16, 2011

Atomoxetine-induced myocardial infarction.

Ali Seifi¹, Heidi Griffith, Sahar Avestimehr

¹Division of Cardiology, Department of Internal Medicine, AtlantiCare Regional Medical Center, Atlantic City, NJ, USA. doctorseifi@gmail.com

Southern Medical Journal

|January 6, 2011

Summary

Atomoxetine, a non-stimulant for attention deficit hyperactivity disorder (ADHD), may pose cardiovascular risks. This case report details atomoxetine-induced myocardial infarction (MI) in a young woman, highlighting potential safety concerns.

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Area of Science:

Pharmacology
Cardiology
Psychiatry

Background:

Atomoxetine is the first non-stimulant medication approved in the US for Attention Deficit Hyperactivity Disorder (ADHD).
Concerns regarding the cardiovascular safety of ADHD medications have led to the development of non-stimulant alternatives.
Limited data exists on the cardiovascular effects of this class of ADHD drugs.

Observation:

A young woman presented with symptoms suggestive of a serious cardiovascular event.
Her medical history included treatment with atomoxetine for ADHD.
The clinical presentation and diagnostic workup were consistent with myocardial infarction.

Findings:

The case suggests a potential link between atomoxetine use and myocardial infarction (MI).
This is a rare but serious adverse event that warrants further investigation.
The patient experienced an MI during atomoxetine therapy.

Implications:

Healthcare providers should be aware of the potential cardiovascular risks associated with atomoxetine.
Further research is needed to elucidate the mechanisms and prevalence of atomoxetine-induced cardiovascular events.
This case highlights the importance of considering drug-induced causes in young patients presenting with MI.