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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Memory impairment in multiple sclerosis and its determinant factors.
1Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran. behnaz.sedighi@gmail.com
Neurosciences (Riyadh, Saudi Arabia)
|January 6, 2011
Summary
Memory impairment affects 71% of multiple sclerosis (MS) patients, worsening with age and disease duration. Regular screening is recommended for these chronic patients.
Area of Science:
- Neurology
- Neuroscience
- Clinical Medicine
Background:
- Multiple sclerosis (MS) is a chronic neurological disease.
- Cognitive impairment, particularly memory deficits, is a common symptom in MS patients.
- Understanding the prevalence and contributing factors of memory impairment in MS is crucial for patient management.
Purpose of the Study:
- To ascertain the prevalence of memory impairment in multiple sclerosis (MS) patients.
- To identify factors influencing the severity of memory impairment in MS.
- To provide data for improved clinical screening and management strategies.
Main Methods:
- A cross-sectional study involving 100 diagnosed MS patients.
- Data collection included demographics, medical history, and neurological examination using the Extended Disability Status Scale (EDSS).
- Memory impairment was assessed using a standard mental status questionnaire.
Main Results:
- A high prevalence of memory impairment was observed, affecting 71% of MS patients.
- Severity varied, with mild to moderate impairment in 35%, moderate to severe in 19%, and severe in 17%.
- Significant correlations were found between memory impairment severity and age, education, disease duration, treatment duration, current medication, and EDSS score.
Conclusions:
- Memory impairment is a prevalent and significant disability in multiple sclerosis.
- Age and longer disease duration are key factors exacerbating memory deficits in MS.
- Intermittent screening for memory impairment is essential for MS patients with chronic disease.
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