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Published on: June 23, 2015
Emphysematous polycystic renal infection.
Y S Sooraj1, G K Nainan, F Joseph
1Department of Nephrology, Lakeshore Hospital and Research Centre, Nettur PO, Kochi, India.
Indian Journal of Nephrology
|January 6, 2011
Summary
Emphysematous infections are rare in autosomal dominant polycystic kidney disease (ADPKD). This case highlights a fatal outcome of emphysematous pyelonephritis with Escherichia coli septicemia in a non-diabetic ADPKD patient.
Area of Science:
- Nephrology
- Infectious Diseases
- Genetics
Background:
- Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited kidney disorder.
- Urinary tract infections (UTIs) are frequent complications in ADPKD patients.
- Emphysematous infections, particularly in the kidneys, are seldom reported in ADPKD.
Observation:
- A non-diabetic patient with ADPKD presented with a severe emphysematous polycystic renal infection.
- The infection was caused by Gram-negative Escherichia coli, leading to septicemia.
- Despite aggressive management, including early nephrectomy, the patient's condition deteriorated.
Findings:
- This case represents a rare instance of emphysematous infection complicating ADPKD.
- Escherichia coli septicemia in this context poses a significant threat.
- Aggressive treatment, including surgical intervention, may not always prevent fatal outcomes in such severe cases.
Implications:
- Highlights the need for heightened awareness of rare but severe infectious complications in ADPKD.
- Suggests that emphysematous infections in ADPKD warrant prompt and aggressive diagnostic and therapeutic approaches.
- Underscores the critical nature of Gram-negative septicemia in ADPKD patients and the challenges in management.
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