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A new gene nested within the dunce genetic unit of Drosophila melanogaster
M Furia1, F A Digilio, D Artiaco
1Dipartimento di Genetica, Biologia Generale e Molecolare, Università di Napoli, Italy.
Abstract:
The molecular organization of the dunce gene of Drosophila melanogaster has proved to be particularly complex, with two divergently transcribed genes, Sgs-4 and Pig-1, nested within its 79 kb intron (1). Here we report the identification and the molecular characterization of a third gene nested within the transcription unit of dunce. This newly identified gene is located nearly 6 kb downstream Pig-1, within a more upstream dunce intron. The gene is developmentally regulated and transcribed with the same polarity of dunce; several lines of evidence indicate that it might encode for a salivary gland secreted (Sgs) protein.