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Updated: Jun 5, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Depression in pregnancy and postpartum period
1MAMTA SOOD, M.D. D.P.M., Graded Specialist (Psychiatry), AX. SOOD, M.D., Classified Specialist (Obstetrics & Gynecology) Military Hospital, Jhansi- 284001.
Maternal depression is common during pregnancy and the postpartum period. Early detection of antenatal depression is crucial as it significantly predicts early postpartum depression.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Mental Health
- Psychiatry
Background:
- Depression during pregnancy and the postpartum period is a significant concern for maternal and infant well-being.
- Understanding the prevalence and incidence of perinatal depression is vital for developing effective interventions.
Purpose of the Study:
- To determine the prevalence and incidence of depression in pregnant women and during the early and late postpartum periods.
- To examine the correlations between depression during pregnancy and the postpartum period.
Main Methods:
- Prospective study involving 84 pregnant patients in their third trimester.
- Beck Depression Inventory administered during the third trimester, within 3 days postpartum, and 4-8 weeks postpartum.
Main Results:
- Prevalence rates of depression were 8.3% (pregnancy), 20% (early postpartum), and 12.8% (late postpartum).
- Incidence rates were 16% (early postpartum) and 10% (late postpartum).
- Antenatal depression significantly correlated with early postpartum depression, and early postpartum depression correlated with late postpartum depression.
Conclusions:
- Perinatal depression is prevalent and requires attention.
- Early detection of depression during pregnancy is critical for identifying women at risk for postpartum depression.
- Findings support the need for integrated mental health care in obstetric settings.
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