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Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

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Related Experiment Video

Updated: Jun 5, 2026

Primary Culture of Dental Pulp Stem Cells
03:45

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Stem cells--prospects in dentistry.

Franziska L Ulmer1, Andreas Winkel, Philipp Kohorst

  • 1Clinic for Dental Prosthodontics and Biomedical Materials Science, Center for Dentistry and Oral Medicine, Medical University of Hannover, Germany. ulmer.franziska@mh-hannover.de

Schweizer Monatsschrift Fur Zahnmedizin = Revue Mensuelle Suisse D'Odonto-Stomatologie = Rivista Mensile Svizzera Di Odontologia E Stomatologia
|January 6, 2011
PubMed
Summary
This summary is machine-generated.

Stem cell research shows potential for dental applications. Adult dental stem cells can regenerate various dental tissues, offering future therapeutic possibilities.

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Primary Culture of Dental Pulp Stem Cells
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Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

Area of Science:

  • Stem cell biology
  • Dental research
  • Regenerative medicine

Background:

  • Stem cell biology offers promising in vitro and in vivo methods.
  • Potential applications in human dentistry are being explored.
  • Adult dental ectomesenchymal stem cells are a focus for future therapies.

Purpose of the Study:

  • To review stem cell research relevant to dentistry.
  • To identify stem cell sources and characteristics for dental applications.

Main Methods:

  • Literature review of stem cell research.
  • Identification of stem cell markers like STRO-1.
  • Analysis of stem cell differentiation potential.

Main Results:

  • Human stem cells isolated from dental pulp, deciduous teeth, periodontal ligament, dental follicle, and dental papilla.
  • Adult dental stem cells can differentiate into dentin, periodontal ligament, cementum, and dental pulp.
  • These stem cells do not differentiate into enamel.

Conclusions:

  • Adult dental stem cells hold significant promise for regenerative dentistry.
  • Further research is needed to fully understand their therapeutic potential.
  • Stem cell-based therapies could revolutionize dental treatments.