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Updated: Jun 5, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Management of acute ischemic stroke: time is brain
Marilyn M Rymner1, Naveed Akhtar, Coleman Martin
1University of Missouri-Kansas City School of Medicine, USA. mrymer@saint-lukes.org
Acute ischemic stroke treatment is time-sensitive and complex. Many US hospitals lack experience with intravenous tissue plasminogen activator (IV tPA), limiting access for stroke patients. Neuro-imaging is crucial for guiding treatment decisions.
Area of Science:
- Neurology
- Emergency Medicine
- Radiology
Background:
- Acute ischemic stroke treatment is critically time-dependent and technically demanding.
- A significant barrier exists in the U.S. for acute stroke treatment, with 64% of hospitals never administering IV tissue plasminogen activator (tPA) and 40% of the population residing in areas without hospitals routinely treating eligible stroke patients with IV tPA.
Purpose of the Study:
- To summarize current acute treatment options for ischemic stroke.
- To discuss the expanding role of neuro-imaging in guiding therapeutic interventions for stroke patients.
Main Methods:
- Review of available acute treatment modalities for ischemic stroke.
- Analysis of the current utilization and impact of neuro-imaging in stroke management.
Main Results:
- Limited accessibility to IV tPA treatment across U.S. hospitals.
- Geographic disparities in stroke care access exist, affecting a large portion of the U.S. population.
Conclusions:
- There is a need to improve hospital preparedness and access to timely stroke interventions like IV tPA.
- Neuro-imaging advancements are increasingly vital for optimizing acute stroke treatment strategies and patient outcomes.
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