Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanistic pathways of dysbiosis in oral cancer development.

Advances in immunology·2026
Same author

Correction: Microbial evaluation of zirconia and titanium implants in the anterior mandibula: a randomized controlled clinical trial.

Scientific reports·2026
Same author

Microbial evaluation of zirconia and titanium implants in the anterior mandibula: a randomized controlled clinical trial.

Scientific reports·2026
Same author

Antibiotic resistance and biofilm forming capacity of supragingival bacteria in healthy and caries patients.

Frontiers in oral health·2026
Same author

Using Selective Agar Containing Ciprofloxacin and Tetracycline Reveals Resistant Oral Microbiota in Healthy and Periodontitis Patients.

MicrobiologyOpen·2026
Same author

Beyond a single species: Mapping virulence traits across the redefined <i>Fusobacterium nucleatum</i> complex.

Virulence·2026

Related Experiment Video

Updated: Jun 5, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

An antimicrobial effect from silver-coated toothbrush heads.

Ali Al-Ahmad1, Margit Wiedmann-Al-Ahmad, Daniela Deimling

  • 1Department of Operative Dentistry and Periodontology, Albert Ludwigs University, Freiburg, Germany.

American Journal of Dentistry
|January 7, 2011
PubMed
Summary

Silver-coated toothbrush heads showed no antimicrobial effect against common oral bacteria in vitro. In fact, higher counts of Streptococcus sanguis and Candida albicans were found on silver-coated brushes, indicating potential harm.

More Related Videos

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

Related Experiment Videos

Last Updated: Jun 5, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

Area of Science:

  • Microbiology
  • Biomaterials Science
  • Dental Hygiene

Background:

  • Toothbrush contamination with microorganisms is a concern for oral hygiene.
  • Silver coatings are explored for potential antimicrobial properties in various applications.
  • The efficacy of silver-coated toothbrush heads against oral microbial colonization requires investigation.

Purpose of the Study:

  • To evaluate the in vitro antimicrobial effectiveness of silver-coated toothbrush heads.

Main Methods:

  • Sixty-two silver-coated and 62 non-coated toothbrush heads were contaminated with standardized microbial suspensions.
  • Microorganisms tested included Streptococcus oralis, Streptococcus mutans, Streptococcus sanguis, Actinomyces viscosus, Lactobacillus casei, and Candida albicans.
  • Colony-forming units (CFUs) were determined after simulated daily toothbrushing and overnight drying.

Main Results:

  • No significant reduction in CFUs was observed for any tested microorganisms on silver-coated toothbrushes.
  • Significantly higher colony counts for Streptococcus sanguis and Candida albicans were found on silver-coated heads.
  • The current silver-coating method did not demonstrate antimicrobial benefits against residual bacteria.

Conclusions:

  • Silver-coated toothbrush heads, in their current form, do not provide antimicrobial benefits.
  • The silver coating may potentially promote the growth of certain microorganisms like S. sanguis and C. albicans.
  • Further research is needed to explore alternative silver-coating strategies or materials for antimicrobial efficacy.