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Dolosigranulum pigrum causing biomaterial-associated arthritis
Bjørn Odd Johnsen1, Else Johanne Rønning, Annette Onken
1Departments of Microbiology, Asker and Baerum Hospital, Baerum, Norway. Bjorn.Odd.Johnsen@oslo-universitessykehus.no
Summary
Dolosigranulum pigrum, a rare bacterium, caused biomaterial-associated arthritis in an immunocompetent patient. This case highlights the importance of considering unusual pathogens in joint infections, even in healthy individuals.
Area of Science:
- Microbiology
- Infectious Diseases
- Rheumatology
Background:
- Dolosigranulum pigrum is a gram-positive, catalase-negative bacterium with a limited history of causing human disease.
- Biomaterial-associated arthritis is a challenging infection often requiring surgical intervention and prolonged antibiotic therapy.
Observation:
- A case of biomaterial-associated arthritis occurred in an immunocompetent patient.
- The causative agent was identified as Dolosigranulum pigrum.
Findings:
- The identity of Dolosigranulum pigrum was confirmed using 16S rRNA gene sequencing.
- The organism was successfully isolated from a synovial biopsy specimen.
Implications:
- This case expands the known spectrum of diseases caused by Dolosigranulum pigrum.
- Highlights the need for considering rare bacteria in the differential diagnosis of prosthetic joint infections and other biomaterial-associated infections.
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