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Published on: February 25, 2014

Dolosigranulum pigrum causing biomaterial-associated arthritis

Bjørn Odd Johnsen1, Else Johanne Rønning, Annette Onken

  • 1Departments of Microbiology, Asker and Baerum Hospital, Baerum, Norway. Bjorn.Odd.Johnsen@oslo-universitessykehus.no

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
|January 7, 2011
PubMed

Insights

Dolosigranulum pigrum, a rare bacterium, caused biomaterial-associated arthritis in an immunocompetent patient. This case highlights the importance of considering unusual pathogens in joint infections, even in healthy individuals.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Rheumatology

Background:

  • Dolosigranulum pigrum is a gram-positive, catalase-negative bacterium with a limited history of causing human disease.
  • Biomaterial-associated arthritis is a challenging infection often requiring surgical intervention and prolonged antibiotic therapy.

Observation:

  • A case of biomaterial-associated arthritis occurred in an immunocompetent patient.
  • The causative agent was identified as Dolosigranulum pigrum.

Findings:

  • The identity of Dolosigranulum pigrum was confirmed using 16S rRNA gene sequencing.
  • The organism was successfully isolated from a synovial biopsy specimen.

Implications:

  • This case expands the known spectrum of diseases caused by Dolosigranulum pigrum.
  • Highlights the need for considering rare bacteria in the differential diagnosis of prosthetic joint infections and other biomaterial-associated infections.

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