Related Experiment Video
Updated: Jun 5, 2026
Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)
Published on: November 29, 2014
Analysis of surface plasmon spectro-angular reflectance spectrum: real-time measurement, resolution limits, and
Colin J Alleyne1, Philip J R Roche, Sandrine Filion-Côté
1Photonic Systems Group, Department of Electrical and Computer Engineering, McConnell Building, McGill University, Montreal, Quebec, H3A 2A7 Canada.
Abstract:
A surface plasmon biosensing technique based on real-time measurement of the spectro-angular reflectance spectrum of a gold surface is presented. A significant improvement in refractive index resolution and drift compensation has been achieved for the spectro-angular technique to demonstrate a biosensing platform that is, in addition, applicable to plasmonic bandgap measurements. Instrumental improvements are detailed and constants for the model bovine serum albumin (BSA):oxacillin bioassay are presented.
