Hypercalcaemia Mimicking STEMI on Electrocardiography

Joseph Donovan1, Mark Jackson

  • 1Royal Sussex County Hospital, Brighton BN2 5BE, UK.

Case Reports in Medicine
|January 7, 2011
PubMed

Insights

Hypercalcemia can cause electrocardiogram (ECG) changes that mimic acute myocardial infarction in low-risk patients. Prompt treatment of hypercalcemia resolved these concerning ECG findings.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Acute coronary syndrome (ACS) is a frequent reason for hospital admission.
  • ST-segment elevation on an electrocardiogram (ECG) typically suggests a cardiac origin, such as myocardial infarction.
  • However, alternative diagnoses must be considered in low-risk individuals presenting with these ECG changes.

Observation:

  • A case is presented of a male patient with hypercalcemia.
  • The patient had no discernible cardiac disease.
  • The patient exhibited ECG changes that closely resembled those of an acute myocardial infarction.

Findings:

  • The observed ECG abnormalities were not due to cardiac pathology.
  • The ECG changes were directly linked to the patient's elevated calcium levels (hypercalcemia).
  • Resolution of the ECG abnormalities occurred following successful treatment of the hypercalcemia.

Implications:

  • Hypercalcemia should be considered in the differential diagnosis of ST-segment elevation on ECG, particularly in patients without clear cardiac risk factors.
  • This case highlights the importance of a comprehensive diagnostic approach, including metabolic evaluation, for patients with ECG changes suggestive of myocardial infarction.
  • Recognizing and treating hypercalcemia can prevent unnecessary cardiac interventions and improve patient outcomes.

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