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Pseudogout Associated Hip Pain in a Patient with HIV Infection
Benan M Dala-Ali1, Matthew Welck, Mary Anne Lloyd
1North Middlesex University Hospital, Sterling Way, London N18 1QX, UK.
Case Reports in Medicine
|January 7, 2011
Summary
A case study reports the first instance of pseudogout in a patient with human immunodeficiency virus (HIV). This finding is significant for orthopaedic surgeons managing HIV patients with joint pain.
Area of Science:
- Orthopaedics
- Infectious Diseases
- Rheumatology
Background:
- Human immunodeficiency virus (HIV) infection impacts millions globally, with potential musculoskeletal complications.
- Orthopaedic surgeons must be aware of HIV's effects on bones and joints.
- The relationship between HIV and conditions like gout, osteonecrosis, and septic arthritis is complex, potentially linked to the virus or highly active antiretroviral therapy (HAART).
Observation:
- A 46-year-old male with a 10-year history of HIV presented with acute hip pain, difficulty weight-bearing, and constitutional symptoms.
- Diagnostic workup included radiological, microbiological, and serological tests.
- Microscopic analysis of hip joint aspirate confirmed a diagnosis of pseudogout.
Findings:
- This is the first reported case of pseudogout in an HIV-infected patient.
- The patient's symptoms resolved completely after joint aspiration and non-steroidal anti-inflammatory drug (NSAID) therapy.
Implications:
- This case expands the known spectrum of musculoskeletal manifestations associated with HIV infection.
- Highlights the importance of considering pseudogout in HIV patients presenting with acute joint pain.
- Further research may clarify the direct link between HIV and pseudogout, distinct from other associated bone and joint conditions.
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