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Pseudogout Associated Hip Pain in a Patient with HIV Infection

Benan M Dala-Ali1, Matthew Welck, Mary Anne Lloyd

  • 1North Middlesex University Hospital, Sterling Way, London N18 1QX, UK.

Case Reports in Medicine
|January 7, 2011
PubMed

Insights

A case study reports the first instance of pseudogout in a patient with human immunodeficiency virus (HIV). This finding is significant for orthopaedic surgeons managing HIV patients with joint pain.

Area of Science:

  • Orthopaedics
  • Infectious Diseases
  • Rheumatology

Background:

  • Human immunodeficiency virus (HIV) infection impacts millions globally, with potential musculoskeletal complications.
  • Orthopaedic surgeons must be aware of HIV's effects on bones and joints.
  • The relationship between HIV and conditions like gout, osteonecrosis, and septic arthritis is complex, potentially linked to the virus or highly active antiretroviral therapy (HAART).

Observation:

  • A 46-year-old male with a 10-year history of HIV presented with acute hip pain, difficulty weight-bearing, and constitutional symptoms.
  • Diagnostic workup included radiological, microbiological, and serological tests.
  • Microscopic analysis of hip joint aspirate confirmed a diagnosis of pseudogout.

Findings:

  • This is the first reported case of pseudogout in an HIV-infected patient.
  • The patient's symptoms resolved completely after joint aspiration and non-steroidal anti-inflammatory drug (NSAID) therapy.

Implications:

  • This case expands the known spectrum of musculoskeletal manifestations associated with HIV infection.
  • Highlights the importance of considering pseudogout in HIV patients presenting with acute joint pain.
  • Further research may clarify the direct link between HIV and pseudogout, distinct from other associated bone and joint conditions.

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