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Neurological involvement in paediatric Behçet's disease
J Metreau-Vastel1, Y Mikaeloff, M Tardieu
1Department of Paediatric Neurology, Bicêtre University Hospital, Le Kremlin Bicêtre, France.
Pediatric Neuro-Behçet's disease (NBD) often presents with severe neurological symptoms, impacting children's learning and schooling. Early educational support is crucial for affected children to manage learning difficulties and visual or concentration disorders.
Area of Science:
- Pediatric Neurology
- Systemic Vasculitis
- Autoimmune Diseases
Background:
- Behçet disease (BD) is a systemic vasculitis with potential neurological involvement.
- Neuro-Behçet's disease (NBD) in children is not well-characterized.
- Understanding paediatric NBD is crucial for timely diagnosis and management.
Purpose of the Study:
- To analyze the clinical presentation of paediatric NBD.
- To evaluate the impact of NBD on children's education and schooling.
- To highlight the need for educational support in affected children.
Main Methods:
- Retrospective chart review of 12 children diagnosed with NBD.
- Phone interviews with patients and physicians to assess physical and schooling status.
- Analysis of clinical patterns and educational repercussions.
Main Results:
- Neurological involvement was identified in 12 out of 40 BD patients (11 years mean age of onset).
- Common neurological manifestations included cerebral venous thromboses and meningoencephalitis.
- Significant sequelae (9/12) and learning difficulties (8/12) were observed, with 6 patients discontinuing education at middle school level.
Conclusions:
- Neurological involvement in paediatric BD is frequent and can have severe consequences.
- Educational accommodations are essential to support children with NBD in their academic pursuits.
- Early intervention and tailored support are vital for managing learning and concentration disorders.
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