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Updated: Jun 5, 2026

Finite Element Analysis Model for Assessing Expansion Patterns from Surgically Assisted Rapid Palatal Expansion
Published on: October 20, 2023
[Correlation between circadian rhythm and rapid palatal expansion]
1Department of Orthodontics, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China.
This study found that the timing of rapid palatal expansion (RPE) activation significantly impacts treatment outcomes, with the best results observed around 9 PM.
Area of Science:
- Orthodontics and Dental Chronobiology
- Investigating biological rhythms in craniofacial development
Background:
- Rapid palatal expansion (RPE) is a common orthodontic procedure.
- Understanding factors influencing RPE efficacy is crucial for optimizing treatment.
- Circadian rhythms, the body's natural 24-hour cycles, are known to influence physiological processes.
Purpose of the Study:
- To explore the relationship between circadian rhythm and the effectiveness of rapid palatal expansion.
- To identify optimal timing for RPE activation based on circadian patterns.
Main Methods:
- 111 patients (55 males, 56 females) undergoing RPE were divided into eight groups based on activation time (every 3 hours from 0 to 21 o'clock).
- Data on tooth movement were analyzed using Halberg methods for cosinor-rhythmometry.
- Statistical analysis included t-tests.
Main Results:
- Tooth movement patterns in response to RPE activation exhibited a clear circadian rhythm, fitting a cosine curve.
- The peak effectiveness (acrophase) for RPE activation was observed around 21:00 (9 PM).
- The lowest effectiveness (bathyphase) occurred around 9:00 (9 AM).
Conclusions:
- Human circadian rhythms demonstrably influence the outcomes of rapid palatal expansion.
- Activating RPE devices around 21:00 (9 PM) appears to be the most effective timing for achieving desired results.
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