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Updated: Jun 5, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
[Depression and personality disorders: mutual influences]
1Clinique de Quissac, Montpellier, France. rimlinger.brigitte@wanadoo.fr
Abstract:
The first disposition described as having an influence on mood date back to ancient Greece. The current modeling of personality disorders is organized essentially in a category-specific logic (DSMIV, CIM-10) and dimensional logic ("big five", Eysenck model, Cloninger model, etc.). The heterogeneity of these evaluation tools affects the readability of the studies concerning the effects of comorbidity on depressive disorders. The frequency of the coexistence of personality disorders/depression (≥50%) which is associated with the severity of the depressive episodes, with pejorative evolutionary prognosis and resistance in treatments, appears to justify a reorganization of classifications in the future DSM-V.
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