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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Microbiome of the Eye01:22

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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

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Related Experiment Video

Updated: Jun 5, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Endogenous endophthalmitis caused by Enterococcus casseliflavus.

Kumar Sambhav1, Annie Mathai1, Ashok Kumar Reddy2

  • 1Smt Kanuri Santhamma Retina Vitreous Centre, L V Prasad Eye Institute, Hyderabad, India.

Journal of Medical Microbiology
|January 8, 2011
PubMed
Summary

Endogenous endophthalmitis caused by Enterococcus casseliflavus is rare. Successful treatment involved vitrectomy and targeted intravitreal vancomycin based on antibiotic sensitivity testing.

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Related Experiment Videos

Last Updated: Jun 5, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Endogenous endophthalmitis is a severe intraocular infection.
  • Enterococcus species are uncommon causes of endophthalmitis.

Observation:

  • A case of endogenous endophthalmitis caused by Enterococcus casseliflavus is presented.
  • The causative organism demonstrated specific antibiotic resistance and sensitivity patterns.

Findings:

  • Enterococcus casseliflavus was identified as the causative agent.
  • The isolate was sensitive to gentamicin, vancomycin, and chloramphenicol.
  • Resistance was noted against cefazolin, ofloxacin, gatifloxacin, and ciprofloxacin.

Implications:

  • This case highlights Enterococcus casseliflavus as a potential pathogen in endogenous endophthalmitis.
  • Sensitivity-based treatment, including intravitreal vancomycin, is crucial for successful outcomes.
  • Understanding antimicrobial resistance patterns is vital for managing this condition.