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A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Moisturizer allergy: diagnosis and management
Matthew J Zirwas1, Sarah A Stechschulte
1Matthew J. Zirwas, MD, is Assistant Professor of Dermatology, The Ohio State University.
The Journal of Clinical and Aesthetic Dermatology
|January 8, 2011
Summary
Many moisturizers contain common allergens like fragrance and parabens, which can cause allergic contact dermatitis. Clinicians should be aware of these ingredients to properly advise patients using topical skin products.
Area of Science:
- Dermatology
- Cosmetic Science
- Allergology
Background:
- Moisturizers are widely used for skin hydration and maintaining skin barrier function.
- While generally safe, moisturizers can cause skin reactions, including allergic contact dermatitis.
- Cosmetic products, particularly moisturizers, are significant contributors to allergic contact dermatitis.
Purpose of the Study:
- To identify and quantify common allergens present in over-the-counter moisturizers.
- To inform clinicians about potential irritants and allergens in frequently used skin care products.
Main Methods:
- Analysis of a database of moisturizers available at Walgreens Pharmacies.
- Identification of allergens based on the North American Contact Dermatitis Group (NACDG) screening panel.
- Quantification of the prevalence of specific allergens across 276 moisturizers.
Main Results:
- Fragrance was the most prevalent allergen, found in 68% of moisturizers.
- Parabens (62%) and Vitamin E (55%) were also common ingredients.
- Other frequent allergens included essential oils, benzyl alcohol, propylene glycol, and formaldehyde releasers.
Conclusions:
- A significant number of moisturizers contain ingredients with the potential to cause allergic contact dermatitis.
- Awareness of these common allergens is crucial for healthcare providers managing patients with skin conditions.
- Informed patient counseling regarding moisturizer ingredients can help prevent adverse skin reactions.
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