[Fast-dissociating complexes of estradiol and corticosterone with rat serum proteins]

The dissociation of estradiol complexes with specific binding proteins of blood sera from 5-day-old and pregnant rats was studied. Two types of complexes differing essentially in their dissociation rates were obtained. The decomposition of fast-dissociating complexes was completed within 30 s. Two classes of corticosterone-binding sites, one of which could form highly labile complexes, were revealed.