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Updated: Dec 29, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
Noneffect of manual needle acupuncture on experimental pain parameters in healthy young men
Peter S Micalos1, Sok Cheon Pak
1School of Human Movement Studies, Charles Sturt University, Bathurst, Australia. pmicalos@csu.edu.au
Objectives:
The purpose of this study is to assess the effect of manual acupuncture on experimental pain parameters in healthy participants.
Design:
The experimental design was a repeated-measures, three-group pre- and postprocedure. All subjects participated in a control, sham, and acupuncture procedure, separated by 1 week, in a counterbalanced sequence to forestall an order effect.
Settings/Location:
Data were collected in a laboratory environment.
Subjects:
The participants included 12 healthy young men (mean age 21.3 ± 2.6 years; height 183.8 ± 5 cm; weight 77.7 ± 9.5 kg).
Interventions:
The control procedure comprised assessing the experimental pain parameters before and after a quiet rest for 20 minutes. The sham procedure was performed with the needle inserted bilaterally 1-1.5 cm outside each acupoint. The manual acupuncture procedure was performed at two bilateral acupoints of LI-4 (Large Intestine 4, Hegu) and ST-44 (Stomach 44, Nei Ting).
Outcome Measures:
Pain parameters assessed included the pain threshold, nociceptive reflex threshold, and nociceptive reflex amplitude.
Results:
Repeated-measures analysis of variance between pre- and postcontrol, sham, and acupuncture procedures for pain threshold, nociceptive reflex threshold, and nociceptive reflex amplitude revealed no significant difference.
Conclusions:
Manual acupuncture at bilateral acupoints LI-4 and ST-44 did not show a change in pain threshold, nociceptive flexion reflex threshold, or the nociceptive reflex amplitude in healthy participants.

