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Updated: Jun 5, 2026
07:16
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
Summary
Researchers isolated known compounds from Zanthoxylum sprucei, including lupeol and hesperidin. The study fully assigned the 1H-NMR and 13C-NMR signals for (-)-cis-N-methylcanadine.
Area of Science:
- Phytochemistry
- Organic Chemistry
- Natural Products
Background:
- Zanthoxylum sprucei is a plant species with potential medicinal properties.
- Previous research has identified various compounds from Zanthoxylum species, but detailed characterization is ongoing.
Purpose of the Study:
- To isolate and identify known chemical constituents from Zanthoxylum sprucei.
- To fully assign the nuclear magnetic resonance (NMR) signals for the alkaloid (-)-cis-N-methylcanadine.
Main Methods:
- Phytochemical investigation involving extraction and isolation techniques.
- Spectroscopic analysis, including 1H-NMR and 13C-NMR, for structural elucidation.
Main Results:
- Seven known compounds were successfully isolated: lupeol, ß-sitosterol, (+)-sesamin, trans-dimethylmatairesinol, hesperidin, (-)-cis-N-methylcanadine, and sucrose.
- Complete assignment of 1H-NMR and 13C-NMR signals for (-)-cis-N-methylcanadine was achieved.
Conclusions:
- The study successfully identified several known compounds from Zanthoxylum sprucei.
- The detailed NMR signal assignment provides valuable data for the characterization of (-)-cis-N-methylcanadine and related alkaloids.
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