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Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

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Published on: February 14, 2011

Control of caseous lymphadenitis.

Peter A Windsor¹

¹Farm Animal and Veterinary Public Health Group, Faculty of Veterinary Science, University of Sydney, 425 Werombi Road, Camden, New South Wales 2570, Australia.

The Veterinary Clinics of North America. Food Animal Practice

|January 11, 2011

Summary

Caseous lymphadenitis (CLA) in sheep, caused by Corynebacterium pseudotuberculosis, impacts global industries. Improved vaccine compliance through enhanced extension programs is crucial for controlling this costly disease.

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Published on: May 19, 2018

Area of Science:

Veterinary Medicine
Animal Science
Infectious Diseases

Background:

Caseous lymphadenitis (CLA) poses a significant economic threat to the global sheep industry.
Corynebacterium pseudotuberculosis is the causative agent of CLA.
Existing vaccination programs have shown limited success in reducing CLA prevalence due to suboptimal compliance.

Purpose of the Study:

To highlight the economic and welfare impact of CLA in sheep production.
To identify poor compliance with vaccination protocols as a key factor limiting CLA control.
To advocate for improved extension programs to enhance vaccine application efficiency.

Main Methods:

Review of CLA prevalence data and vaccination program effectiveness.
Analysis of factors contributing to suboptimal vaccine compliance in sheep producers.
Assessment of current extension program strategies for disease control.

Main Results:

Despite long-standing vaccination availability, CLA prevalence decline has been slower than anticipated.
Non-adherence to booster vaccinations in lambs and annual vaccinations in adults is a primary concern.
Current extension approaches may not be sufficiently effective in promoting consistent vaccine application.

Conclusions:

Effective control of CLA requires addressing producer compliance with vaccination schedules.
Evolution of best practice extension programs is essential for efficient vaccine use.
Targeted interventions are needed to improve lamb and adult sheep vaccination rates to mitigate economic losses.