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Updated: Jun 5, 2026
06:49
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
Bilateral arteritic anterior ischemic optic neuropathy
Michelle Matson1, Lane Fujimoto
1Veterans Affairs Southern Nevada Healthcare System, Las Vegas, Nevada 89036, USA. michelle.matson3@va.gov
Optometry (St. Louis, Mo.)
|January 11, 2011
Summary
Arteritic anterior ischemic optic neuropathy (AION), often caused by giant cell arteritis, requires prompt corticosteroid treatment to prevent vision loss. Early diagnosis by optometrists is crucial for managing this ocular emergency.
Area of Science:
- Ophthalmology
- Rheumatology
- Vascular Medicine
Background:
- Arteritic anterior ischemic optic neuropathy (AION) affects individuals over 50, typically linked to giant cell arteritis.
- Prompt corticosteroid therapy is vital to avert severe vision impairment.
Observation:
- A 63-year-old male presented with bilateral blurred vision and visual field loss.
- Ocular examination revealed swollen optic nerve heads and altitudinal defects.
- Laboratory tests indicated elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP).
Findings:
- The patient received oral prednisone for arteritic AION.
- Follow-up showed reduced ESR and CRP levels.
- Optic nerve swelling decreased, and visual fields stabilized.
Implications:
- Arteritic AION is an emergent condition requiring rapid diagnosis and intervention.
- Optometrists play a key role in identifying and initiating treatment for arteritic AION.
- Timely corticosteroid administration is essential for preserving vision in arteritic AION cases.
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