Related Experiment Video
Updated: Jun 5, 2026
Direct Cannula Implantation in the Cisterna Magna of Pigs
Published on: June 9, 2021
Primary meningeal hemangiosarcoma in a grower pig
Ingo Spitzbarth1, Martin Peters, Alexandru C Stan
1Department of Pathology, University of Veterinary Medicine, Bünteweg 17, D-30559 Hannover, Germany.
A rare primary meningeal hemangiosarcoma was diagnosed in a juvenile pig. This vascular tumor infiltrated the olfactory bulb, indicating a serious condition in swine.
Area of Science:
- Veterinary Pathology
- Comparative Oncology
- Swine Neoplasia
Background:
- Neoplasms of the central nervous system (CNS) are uncommon in pigs.
- Meningiomas are the most common primary CNS tumors in dogs, but hemangiosarcomas are rare.
Observation:
- A juvenile female pig presented with a focal, red meningeal mass (3.5 cm) over the left olfactory bulb.
- Histopathology revealed polygonal-to-spindle cells forming vascular clefts with neuropil invasion.
Findings:
- Immunohistochemistry showed strong vimentin expression.
- Variable expression of factor VIII-related antigen, smooth muscle actin, and neurotrophin receptor p75 supported vascular and smooth muscle origins.
- The tumor was diagnosed as a primary meningeal hemangiosarcoma.
Implications:
- This case highlights the importance of considering vascular tumors in differential diagnoses for CNS masses in swine.
- Further research into the specific markers and behavior of hemangiosarcomas in pigs may improve diagnostic accuracy.
- Understanding such rare neoplasms contributes to the broader field of comparative oncology.
More Related Videos
08:38Exposure of the Pig CNS for Histological Analysis: A Manual for Decapitation, Skull Opening, and Brain Removal
Published on: April 13, 2017
11:06Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care
Published on: November 11, 2022