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Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR
Published on: July 22, 2012
Rotavirus enteric infection in children of northwest Iran
Ziaaedin Ghorashi1, Afshin Ghalehgolab Behbahan, Shahram Abdoli Oskouei
1Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
Rotavirus is a common cause of acute gastroenteritis in children under 36 months, frequently requiring hospitalization during colder months. This study highlights its prevalence in young children admitted to Tabriz Children
Area of Science:
- Pediatrics
- Infectious Diseases
- Virology
Background:
- Acute gastroenteritis is a significant cause of childhood morbidity worldwide.
- Rotavirus is a leading viral pathogen responsible for severe diarrheal disease in infants and young children.
- Understanding the epidemiology of rotavirus in specific geographic regions is crucial for public health interventions.
Purpose of the Study:
- To determine the prevalence of rotavirus in children under 36 months with acute gastroenteritis.
- To analyze the seasonal distribution and hospital stay duration associated with rotavirus infections.
- To provide data for potential rotavirus vaccination strategies in the region.
Main Methods:
- A cross-sectional, analytical-descriptive study design was employed.
- Stool specimens were collected from 511 children under 36 months admitted with acute gastroenteritis.
- Rotavirus detection was performed using laboratory diagnostic methods.
Main Results:
- Rotavirus was identified in 55.6% (284/511) of the children studied.
- The majority of rotavirus cases (two-thirds) occurred during autumn and winter seasons.
- The average hospital stay for children with rotavirus gastroenteritis was 3.1 ± 1.8 days.
Conclusions:
- Rotavirus is highly prevalent among young children hospitalized for acute gastroenteritis in Tabriz.
- Seasonal peaks in autumn and winter suggest a pattern of transmission that warrants attention.
- The findings underscore the burden of rotavirus disease and the potential benefit of rotavirus vaccination programs.
Abstract:
This is a cross-sectional and analytical-descriptive study of 511 children less than 36 months of age who were admitted to Tabriz Children's Hospital with acute gastroenteritis during a period of 2 years (from October 2007 to October 2009). Rotavirus was found in stool specimens of 284 (55.6%) of 511 children with diarrhea. Two-thirds of them were admitted during autumn and winter for a mean hospital stay of 3.1 ± 1.8 days.
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