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Bronchiectasis in children: 10-year experience at a single institution
Hyoung-Young Kim1, Ji-Won Kwon, Juhee Seo
1Department of Pediatrics, Childhood Asthma & Atopy Center, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.
Allergy, Asthma & Immunology Research
|January 11, 2011
Summary
Investigating pediatric bronchiectasis in Korean children revealed diverse causes like bronchiolitis obliterans and respiratory infections. Identifying these underlying factors significantly impacts patient management and prognosis.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Clinical Epidemiology
Background:
- Bronchiectasis is a significant cause of childhood mortality in developing nations.
- Understanding its characteristics is crucial for effective intervention.
Purpose of the Study:
- To investigate the epidemiology, clinical features, and etiologies of pediatric bronchiectasis.
- To assess changes in management based on identified causes.
- To analyze findings at a tertiary referral center in Seoul.
Main Methods:
- Retrospective study of children diagnosed with bronchiectasis (1999-2008).
- Comprehensive examination to identify etiologic factors.
- Analysis of age, symptoms, etiology, treatment changes, CT findings, and microbiology.
Main Results:
- Median age at diagnosis was 7.6 years; persistent coughing was the most common symptom.
- Identified etiologies included bronchiolitis obliterans (32.6%), childhood respiratory infection (20.6%), and interstitial lung disease (17.3%).
- Underlying causes led to individualized management changes in 67% of patients; CT findings did not correlate with etiology.
Conclusions:
- Diverse underlying etiologies for pediatric bronchiectasis were identified in Korean children.
- Comprehensive investigation for underlying causes is essential for optimizing management and prognosis.
- Early diagnosis and etiological identification are critical for improving outcomes in pediatric bronchiectasis.
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